Seen On X-itter — So Take It All With A TRUCKLOAD Of Salt… Incyte To Be Acquired By Merck? I For One Doubt It…

Separately, we can confirm definitively that Merck has boosted its quarterly dividend — to $0.81/share — starting in January 2025, though. [That’s good news for long term holders, to be sure — even with the less than stellar tax effect, of paying cash dividends in US companies.]

But let’s put this one in the category of… not terribly… likely.

There would be little reason for Rahway to need to own the whole cow — when it will always be able to access just the cups of milk it most desires, as a rule.

Yep — it is a repeated rumor — based off of a rumor, thus:

…Mark Kleinman, Sky News’ City editor, posted on X, the service formerly known as Twitter: “Revealed: Merck, the US-listed pharma group, is the latest industry giant to be linked to a takeover bid for Incyte, with which it collaborates on several drug development projects. Merck has a market cap of $244bn, while Incyte is valued at nearly $15bn.

Both refused to comment….”

As we always say — “never say never…” but I am a skeptic here. But do bet on that fat dividend — now approaching 4% a year. Grin — now… go Buffs, beat the Jayhawks!

नमस्ते

Hinderaker: Reporter of Rumors, Complaining Anout… Reporting, Of Rumors… Hmm.

This… is precious.

Hinderaker, who said the “dying was mostly over” in July of 2020, as to COVID (based on a rumor his health insurance former GC had told him) with about 30,000 deaths — and it went on to twenty times that figure.

And then there is the near-daily drivel, that his good buddie Steve Hayward offers (here three weeks ago, claiming WW III was underway).

Damn.

Out.

Another Day; Another Non-Compliant Letter “Motion”; Another Smackdown, From USDC Judge Liman, In Manhattan — Rudy Chronicles, Continued.

Well… surprising no one who’s been paying much attention, Mr. Giuliani’s Staten Island lawyer was — for the second time in as many days — told to learn how to file motions, in Manhattan’s federal district courts.

He keeps dashing off very informal letters (which leave some ambiguity as to whether the statements have been verified by the lawyer, or are made, effectively under oath by Rudy hisself). That is why Manhattan local rules require formal motion practice: to prevent a lawyer (or a client) from later saying “Gee, I did not know that was a false statement to the court!”

In any event, the new Rudy four page letter (which I won’t link) sought to require Judge Liman to set aside about $210,000 from any sale proceeds, from the NY Co-Op property, at right — to be sure Rudy could get what the lawyer styled as “a homestead exemption” in one of either NY or Florida — in cash.

That motion — even if ultimately made properly — will fail. Rudy’s only chance now, now that he’s voluntarily turned over the NY place — is to get the Florida place exempted. But even then, he couldn’t claim cash back from the plaintiffs here — he would just be allowed to keep living in the Florida place (or sell it himself, and generate cash — but then the cash could be attached, excepting only about $6,000 worth) — as non-exempt asset, subject to the prior turnover orders, already entered.

Rudy will never have substantial assets again, in life — (absent winning the Mega-Millions!) he’ll never be able to pay off the $148 million he owes — plus interest. [And every time he gets some cash, the Georgia poll workers / mother daughter will get all but 34% of it, as garnished “wages”.] He will have to live on only about 15% of what he brings in, as he will owe federal, and state, income taxes on the full amount, but be required to pay them out of his 34% allowances. Forever. And ever.

[To be clear, this would assume he can generate, at a gross level, over $200,000 a year on the radio, or in appearances at MAGA events. OTOH, if he is only earning under $60,000 a year, then his “allowance” will be higher, and his tax burden… lowered — but his net take-homes will put him very near the poverty line. Forever.]

Couldn’t happen to a nicer guy.

Onward.

Power Alley: While A Bit Behind — On The FDA Approval Calendar — Compared To Roche’s Tecentriq®, and BMS’s Opdivo®, Keytruda® Scored A Win — In A Subcutaneous (i.e., Long Acting) Delivery Form

This will undoubtedly expand the use of the blockbuster (in certain lung cancers), especially in parts of deeply-rural America (and later, around the world) — for people who live several hours away from any major teaching hospital or cancer center. Having to drive ten hours or more — or fly about every week — or every other one — can be a logistical / financial deal-breaker. This opens the probability of only making the trip once every three months.

Here’s the whole story, from the irrepressible FiercePharma — and a bit:

…Two months after Roche scored an FDA approval for its subcutaneous version of PD-LI inhibitor Tecentriq, Merck has achieved a key milestone in lining up its checkpoint inhibitor Keytruda to follow suit.

On Tuesday, company revealed that its subcutaneous formulation of Keytruda has aced a phase 3 trial, demonstrating non-inferiority to the immunotherapy’s intravenous version….

[S]ubcutaneous Keytruda — which includes Alteogen’s berahyaluronidase alfa, an enzyme used to improve the absorption and dispersion of drugs and other agents — was given to metastatic non-small cell lung cancer patients along with chemotherapy. Another group of patients received IV Keytruda and chemotherapy….

Gaining approval for subcutaneous Keytruda would expand access for the world’s best-selling drug, which racked up sales of $25 billion last year. In its IV form, Keytruda is administered at infusion centers, with the procedure taking approximately 30 minutes, every three to six weeks….

Now you know — and on, to loads of Cajun Lobster, and Shrimp tonight! Woot!

नमस्ते

Hinderaker: Again, Urging Everyone To Just Be… His “Good Germans”… Hard Pass.

The guy has completely… lost it.

He thinks that we all (based on the fact that a good part of Low Information America® voted for him)…

…must now bow, and pay homage… to the dotard.

Me? Hard pass.

I’m gonna’ resist — within the bounds of the law. And, to the very limits… of the law. Just like 2017 to 2021.

Buckle up, John… we will use the courts to grind your purported new Reich… to dust.

And the fact that he lost the popular vote… again, it matters. To me.

Cheers, chucklehead.

The ESA / Rosetta / Philae Comet Landing — Ten Years On: A [Very Fond] Look Back.

We covered this closely, for a year — almost exactly a decade ago, now. And what a time it was — even though the lil’ lander ended up laying in a shadow on its side.

It was then largely “missing” — from mid November of that year, until early January, of the next– when it was spotted again. Here’s a reminder of what all went down — for advancing celestial object science, and exploration:

…[In November 2014], after a ten-year journey through the Solar System and over 500 million kilometres from home, Rosetta’s lander Philae made space exploration history by touching down on a comet for the first time. On the occasion of the tenth anniversary of this extraordinary feat, we celebrate by taking a look back over the mission’s highlights.

Rosetta was an ESA mission with contributions from its Member States and NASA. It studied Comet 67P/Churyumov-Gerasimenko for over two years, including delivering lander Philae to the comet’s surface. Philae was provided by a consortium led by DLR, MPS, CNES and ASI… [with a video below narrated with a lilting Gaelic brogue, too!].

Now you know. what a time, indeed — a bumpy ride, going into those weeks here on Jasoom, as well — as we swirled between craggy law firms’ managing partners — and, in truth, various people — some still in the shadows, as well. What a time, indeed.What a time, indeed.

नमस्ते

No Way To Know If A Deal Was Reached — But Eddy Grant Had Tangerine’s People “At Bargaining Table” This Morning.

In Manhattan, there has been a settlement conference — to hammer out the damages Team Trump owes Eddy Grant for stealing “Electric Avenue” — in a campaign ad, from the last election cycle (2020).

The court long ago ruled this was a case of willful, unlawful infringement, by the Trump 2020 Campaign.

And now the main issue is how much does the RNC/Tangerine owe to Mr. Grant:

Minute Entry for proceedings held before Magistrate Judge Henry J Ricardo: Telephone Conference held on 11/18/2024. (rdz)….

We wait to see — if a settlement agreement emerges on the docket in Manhattan, in the coming weeks (or months).

Onward, smiling… in spite of myself.

Ever… onward.

नमस्ते

Mr. Giuliani’s Staten Island Lawyer… Gets Schooled — By USDC Judge Liman. Most Of His Four Page Letter: DENIED.

Scant surprise here. US District Court Judges in Manhattan are — in general — a very hard-boiled lot. They’ve seen it all before: the bluster, the bravado… the impotent chutzpah.

This is one of those cases. That four page motion/letter I posted on Friday — from Mr. Giuliani’s new lawyer… landed, with a sickening thud. It has now fallen — as a largely dead letter. Do see the below, from the immensely able USDC Judge Liman — just entered on the docket:

. . .To the extent that Defendant requests an extension of deadlines that would expire prior to November 26, 2024, that request is denied. All deadlines remain in place.

To the extent that Defendant’s letter requests additional relief beyond an extension and substitution of counsel, those requests must be made by formal motion and will be disregarded as expressed in the letter at Dkt. No. 121. The Court refers counsel to the Court’s Individual Practices in Civil Cases for guidance….

(Signed by Judge Lewis J. Liman on 11/18/2024)….

There is deliciously sublime irony at work here — seeing the once mighty Rudy, humbled before the law he used against so many of limited means, across decades of his career as a prosecutor — and then Mayor — of the Apple. Onward.

नमस्ते

Another Reason To Oppose Kennedy — As Health Secretary: His Mindless Promotion Of “Raw Milk”, To Low Information Americans…

Yes — there are some fairly safe ways to (carefully, scientifically) consume milk that has not been pasteurized — that is true. But this, in and of itself, requires a very clear under- standing of the bio-science behind why we do almost universally pasteurize milk.

And frankly, my central concern here is that if these are the low information Americans that (got fleeced by, and) voted for Tangerine (twice, now!) — they aren’t particularly likely to be capable of understanding, let alone… of critically investigating the science — and designing all the pro-active, precise steps required… to make so-called “raw” milk safe for kids to consume in the home. If nothing else, one must be absolutely certain that every link in their personal supply chain (unless this is a single-family farm, run exclusively and directly by family members versed in bio-science, for their kids and themselves) is doing it exactly right — every time.

Otherwise, there is a fairly strong chance that the kids will at a minimum suffer stomach ailments, or worse — get a very dangerous bacterial infection — and need says or weeks of hospitalization. So — for a small segment of very well-educated people, raw milk locally sourced, may offer some rather modest natural immunity boost.

But for the vast bulk of people who’ve simply bought into the anti-vax nonsense (because they are prone to believing everything other Trumpers say, or a general lack of curiosity — and affinity for vague conspiracy theories) — this is a real and present danger, from a public health standpoint. One Mr. Kennedy is likely to exacerbate, if he’s granted a hearing and confirmed. Let’s listen in to Prof. Devi Sridhar, the chair of global public health at the University of Edinburgh in Scotland — a highly regarded science expert on it all, via this morning’s UK Guardian:

…Similarly, [Mr. Kennedy] has tweeted about the benefits of raw milk, which has become a bizarre MAGA talking point generally. Raw milk consumption is a risk factor for a number of dangerous illnesses from E coli to salmonella, but is even more worrying with the widespread infection of dairy herds in the US. While pasteurisation has been shown to kill the H5N1 virus in milk and prevent its ability to infect, raw milk obviously retains all the original pathogens.

This year, 24 cats who drank raw milk on a farm become infected by avian flu; 12 died and 12 suffered from blindness, difficulty breathing and other serious health problems. This is when we need federal agencies to regulate what is being sold to the public and ensure clear communication of the health risks.

Instead, raw milk demand has gone up, with some vendors claiming that “customers [are] asking for H5N1 milk because they want immunity from it”. (There’s a certain irony in the logic behind vaccination – training our immune system in how to respond to a pathogen – being used in this situation)….

So it is, in many areas of our life-times — we are wildly lucky to be alive, in an era of great advances in the sciences, generally. But as the old saying goes, you can lead a horse to water, but you cannot make it drink.

The idea that real science may need to effort “PSAs” — to keep low information Americans safe — from their own (possible future) Secretary of Health (and counter his own mis-information!)… in 2024 and beyond… is just gob-smacking. Onward, just the same on a warm gray rainy Monday morning here — to the steel and glass canyons.

नमस्ते

The Level Of Lunacy Among MAGAts… Is Astonishing. Here’s Exhibit “C” — For [California] Cardiology.

This jamoke — in Paul’s comment section — equates Rep. Matt Gaetz… an elected leader, and proposed top lawyer in the US government, with a private citizen, with admitted addiction issues — to say that if the DoJ did not indict Gaetz… he should be considered fit to serve, as actually innocent of sex-trafficking and drug use charges — which are the subject of a forthcoming US House Committee Ethics report (controlled by his own GOP).

Me? I’d never want to be near this cardiologist, for my care — as that “opinion” of his… completely undermines my faith in his reasoning abilities.

Here’s his bio (to be fair — some pedigree there, at Yale Med School):

Daniel Wohlgelernter, M.D.

…Dr. Wohlgelernter earned his medical degree from the Yale University School of Medicine in New Haven, Connecticut. He completed his internship and residency in Internal Medicine, as well as a fourth year as chief medical resident, at the Yale Medical Center.

He trained in cardiology at Yale, and served on the Yale medical school faculty for two years before joining the UCLA faculty in 1985. He is Board Certified in Internal Medicine and Cardiology (Cardiovascular Disease). He is a Fellow of the American College of Cardiology.

Dr. Wohlgelernter has authored numerous medical journal articles and textbook chapters on a variety of topics pertaining to the diagnosis and treatment of heart disease. His special interests include preventive cardiology, management of lipid disorders and hypertension, and noninvasive management of arrhythmias.

Dr. Wohlgelernter was a recipient of The Thomas L. Stern, M.D. prize for excellence in teaching, awarded by the Santa Monica-UCLA Medical Center Family Practice Residency Program. He has been acknowledged as a Southern California Super Doctor every year since 2008. He has been featured as one of California’s ‘Top Doctors” every year since 2015. Dr. Wohlgelernter has also appeared on The Discovery Channel as a cardiology commentator.

Dr. Wohlgelernter offers a concierge program that allows him to provide in-depth medical services and extra time for his patients. As your concierge doctor, Dr. Wohlgelernter will serve not only as your cardiologist, but also as a motivator and trusted counselor, to help you build a heart-healthy lifestyle. Dr. Wohlgelernter’s approach is based on the concept that healing is a partnership with the patient, who is cared for as a whole person. Patients receive all the care they need and none that they do not….

Now you know. Y I K E S. . . Out.