A Return To The Power Alley: Phase I/II Trial Now Dosing, For “Sudan Variant” Ebola Vaccine Candidate: Per IAVI

As we have long reported (see any of over 400 posts at the main site; search “ebola” in the box at upper left on the main site), there is/was no approved vaccine for the Sudan strain that struck Uganda and South Sudan in outbreaks, last fall. [And it does seem… equitable, that the leading risk, to the extent there is one, be from time to time shouldered by first volunteers here in the states.] And to be sure, this is what true blue patriotism looks like, as we approach the Fourth again.

Jumping back to Uganda in 2022, and thankfully so, the outbreak was arrested in early stages by rapid detection and isolation. So rapid, in fact, the vaccine candidate could not reach the front-lines in time to be tested in ring-fashion. So now, 36 brave, healthy US volunteers, with no known exposure to any version of Ebola have been dosed with the experimental candidate — and will be followed for six months. Here’s the latest:

…A vaccine candidate for a type of Ebola virus has been administered to human beings for the first time, the International Aids Vaccine Initiative (IAVI) has announced.

The first participants in this trial were vaccinated in the United States this week. IAVI said in a statement that about 36 healthy adults will be enrolled and followed for six months after vaccination to monitor their safety and immune responses….

To be certain, this is good news — and is how solid pandemic amelioration science works. Kudos to those willing to be first “test pilots” on this initiative. May they — and we all — be rewarded, with a new tool to save lives in sub-Saharan Africa.

Onward, smiling — ever onward.

नमस्ते

Meanwhile, In Actually IMPORTANT “Espionage-By-Former-POTUS” News…

The Powerliners have whined about some tangential remarks made by a low level IRS employee, claiming to be a whistle-blower. Remarks about a person who has never held any office, at any level — nor any executive role in any political party. Unfortunate — but small potatoes — for which he has accepted responsibility. Whatever, boys.

Here is what it is all intended to deflect from: Tangerine personally showing highly classified stolen documents (in this case, a map) to a Trump-aligned PAC executive in mid-2021, at his club.

She will be called to testify, in his felonies trial. And Tangerine will… indeed, burn (per ABC):

…Susie Wiles, one of Trump’s most trusted advisers leading his second reelection effort, is the individual singled out in Smith’s indictment as the “PAC Representative” who Trump is alleged to have shown a classified map to in August or September of 2021, sources said.

Trump, in the indictment, is alleged to have shown the classified map of an unidentified country to Wiles while discussing a military operation that Trump said “was not going well,” while adding that he “should not be showing the map” to her and “not to get too close….”

So — to recap: Trump stole top secret documents, and then knowingly, intentionally, waved them about over a year and a half after he left office, describing the content of the same to a high ranking political party operative, solely for use in a political operation — against the currently serving opposition party (Democratic) POTUS.

Damn… Power-boys: where is your outrage, about THAT?!

Erh… Honestly… So, What? YAWN.

Justices Sotomayor and Jackson (in dissents, at page 68, as one example) have the better of the arguments. That much is certain.

And yes, this is indeed a disappointing bit of unhinged activism — by the increasingly radical conservative wing, untethered from real world, lived experiences of people of color.

But it is silly to think it changes… much. As the Sotomayor dissent makes plain below, colleges have a myriad of other, still plainly lawful tools — to make sure that people of limited means, and diverse backgrounds are seated at the nation’s most coveted institutions of higher learning.

In short, life will go on. And the frothy hard right will be unable to do much of anything about it. The arc of the moral universe… will still bend toward… progress, for peoples descended from those enslaved by those who now (at least in some measure) will seek, and fill the seats that might previously have been available to a person whose own great grand-parents fought their way out of bondage. Yes, life will go on. Here’s the opinion, and the dissent:

…At its core, today’s decision exacerbates segregation and diminishes the inclusivity of our Nation’s institutions in service of superficial neutrality that promotes indifference to inequality and ignores the reality of race….

Notwithstanding this Court’s actions, however, society’s progress toward equality cannot be permanently halted. Diversity is now a fundamental American value, housed in our varied and multicultural American community that only continues to grow. The pursuit of racial diversity will go on. Although the Court has stripped out almost all uses of race in college admissions, universities can and should continue to use all available tools to meet society’s needs for diversity in education. Despite the Court’s unjustified exercise of power, the opinion today will serve only to highlight the Court’s own impotence in the face of an America whose cries for equality resound. As has been the case before in the history of American democracy, “the arc of the moral universe” will bend toward racial justice despite the Court’s efforts today to impede its progress. Martin Luther King “Our God is Marching On!” Speech (Mar. 25, 1965)….

[And, Justice Jackson:] Do not miss the point that ensuring a diverse student body in higher education helps everyone, not just those who, due to their race, have directly inherited distinct disadvantages with respect to their health, wealth, and well-being. Amici explain that students of every race will come to have a greater appreciation and understanding of civic virtue, democratic values, and our country’s commitment to equality. The larger economy benefits, too: When it comes down to the brass tacks of dollars and cents, ensuring diversity will, if permitted to work, help save hundreds of billions of dollars annually (by conservative estimates)….

Somehow this dark gray (wildfire driven) hazy sky — not luminous at all, but solely. . . stultifying, seems an apropos set-backdrop — on a morning where the largely lily whyte radical right wing of the court… told kids who struggle against odds the court’s own lilly whyte nephews and nieces never even have to witness, let alone endure. . . that “we six find your experiences not worthy of consideration, at all”. The six dismissed them, out of hand. Damn. But yet and still… they will… rise.

Onward. Ever, onward.

नमस्ते

Paul Mirengoff Ought To Just Admit It: Trump’s Brand Of “Populism” Is Anti-Democratic. Period.

Tonight, obviously lacking anything useful to say, Paul decides to go after a former CoC (44), about remarks on how our vast and widening wealth gaps in America make our democracy less stable. No sensible person disputes this.

So, instead of making any real, measured argument, Paul goes all 19th Century — and says (in a time when many — perhaps 3/5ths of us… could not even read!) “the democracy” held together in the time of robber barons. Well — yes… mostly true, because tens of millions were functionally enslaved and twenties of millions were… indentured to the robber barons.

So, I guess his “argument” (such as it is) is that we should stop the information economy, all move out on to dirt roads with no phone lines, internet or newspapers. Sure — that’s a “more stable”… something — but it is NOT democracy. Democracy dies… in such darkness. A literate electorate is the best defense against the tyranny of Tangerine, in truth.

In fact, falling literacy… now, that is the recipe for a… revolution (or J6 mayhem more precisely) — it always has been. See, Marie Antoinette.

As if to prove he knows he’s making an insipid argument — he offers this up, himself — voluntarily, about Trump’s time (2016-2020):

…Polling in 2020 found that the higher a person’s income, the more likely they were to say the economy would improve more in a second term of Trump than under Joe Biden. In the 2020 election, Trump did better among voters making more than $50,000 per year than he did among voters making less than $50,000 per year….

So… his criticism of Mr. Obama in fact accepts the truth of what Barack said.

He just doesn’t like what it means for 2024, and Trump — who may well be running from a jail cell in the general in 2024.

Bub-bye, Paulie.

“Managing What The Elephant Sees…” Now, There’s An FBI Agent Scandal!

Damn.

Here’s an actual scandal.

This is all nearly immediately prior to J6.

By A MAGA-loyte.

Inside FBI — go read EmptyWheel on it all:

…D’Antuono (an FBI agent, and Trumper), we’ve since learned, repeatedly tried to limit the investigation in the aftermath, playing a key role in thwarting any investigation into Trump’s actions for ten months.

Manage the elephant [the wider federal government] by controlling what it sees and hears….

Damn. Check that, Betsy and John.

Crazy Old Betsy… Again.

Let’s just stipulate: the whole “whistle-blower” narrative — Bitsy’s shiny new bauble (along with GOP Sen. Grassley’s fawning credulity) — even if literally true (a dubious proposition, at that)… amounts to… nothing.

There is a plea agreement, kids. [And this scolding applies with equal force to Scott Johnson, as well, this morning.]

You Powerliners don’t seem to be willing to let criminals accept public responsibility.

Which explains why you all fell silent in 2020 when Tangerine PARDONED felons who helped him keep power.

GOP: the party of feckless, self-washing felons, everywhere.

What a… winning brand!

Yikes.

A 2028-Era Space Agencies’ “Marvel Team Up”… Is A’ Comin’ To a Cosmos… But Not So Near You, At L2.

This stuff always lights my imagination, and helps to inspire. . . my passions.

In early 2028, when the NASA Roman space telescope settles in and cools down, at L2, it and the Euclid mission, from the European Space Agency (we have followed Euclid here, for over two years), will work in tandem to increase the power of the science in both missions.

“That is how we do this“, folks — just like Milo Morales’ team-ups in the Spider-verse. Heh — here’s a bit:

…The universe has been expanding ever since its birth – a fact discovered by Belgian astronomer Georges Lemaître in 1927 and Edwin Hubble in 1929. But scientists expected the gravity of the universe’s matter to gradually slow that expansion. In the 1990s, by looking at a particular kind of supernova, scientists discovered that about 6 billion years ago, dark energy began ramping up its influence on the universe, and no one knows how or why. The fact that it’s speeding up means that our picture of the cosmos is missing something fundamental.

Roman and Euclid will provide separate streams of compelling new data to fill in gaps in our understanding. They’ll attempt to pin down cosmic acceleration’s cause in a few different ways.

First, both Roman and Euclid will study the accumulation of matter using a technique called weak gravitational lensing. This light-bending phenomenon occurs because anything with mass warps the fabric of space-time; the bigger the mass, the greater the warp. Images of a distant source produced by light moving through these warps look distorted, too….

“Euclid’s first look at the broad region of sky it will survey will inform the science, analysis, and survey approach for Roman’s deeper dive,” said Mike Seiffert, project scientist for the NASA contribution to Euclid at NASA’s Jet Propulsion Laboratory.

“Together, Euclid and Roman will add up to much more than the sum of their parts,” said Yun Wang, a senior research scientist at Caltech/IPAC in Pasadena, California, who has led galaxy clustering science groups for both Euclid and Roman. “Combining their observations will give astronomers a better sense of what’s actually going on in the universe….”

Indeed — platonic team-ups are a… good thing! Now you know — as the haze and raw choking feeling eases a bit here, this afternoon. Smile.

नमस्ते

With Three Forceful New Supremes’ Decisions (Striking the Invidious MS, LA And NC Maps), It Is Clear The Court Will Not Allow A Return To Jim Crow By A Gerrymandering State Level GOP…

There were solid majorities (in the past two weeks), even inside the GOP appointed US Supreme Court wing, to vote in support of the notion that even in ruby red, GOP controlled states, these state-level legislatures and governors cannot ignore the commands of the federal 14th Amendment. In sum, the preposterous MAGA claim that state-houses alone get to decide what a “fair racial map” looks like… is now effectively… dead. [Didn’t these jokers read Marbury v. Madison in high school?!]

Because in nearly every case, the gerrymandering attempts sought to dilute cognizable brown and Black voting power, it is plain the GOP sought a return to Jim Crow, albeit in white velvet gloves.

With the highest court quashing these odious efforts, it is very likely that the state level GOP organizations will see losses on the national stage, in general elections in 2024.

In fact, when this SCOTUS impact is amplified by the wave seen in local Virginia primaries last week, the GOP as a brand may be… in danger of dying out. The most straight-forward reading of Virginia’s Summer 2023 results is that whyte suburban college-educated married women in red or purple states are abandoning their decades long GOP voting patterns, in a ferocious protest voting bloc — against the oozing, dripping misogyny embedded in last year’s Dobbs decision.

Can’t say we didn’t warn those doddering, embittered old whyte male coots who pretend to run national politics.

Their time draws to an end, now — it would seem. Smiling… even though our throats are quite raw here, in the pale orange haze of this morning, in the City of Big Shoulders — due to a second wave of Canadian forest fires’ smoke plumes… ugh. Onward.

नमस्ते

Finally! Something Hayward Is… RIGHT About!

Of course, it would only be a “Lowest Common Denominator” type thing.

Steve tonight says “no one” can really say what’s going on — in Russia.

Is Putin… truly in control? Or is he being stage-crafted toward the exit, as generals and oligarchs barter with forces in Belarus?

Will that be the new power center?

Or will it all just remain entirely… opaque?

Indeed, we civilians don’t know.

But our CIA likely does. And Mr. Biden does.

And what is known is that Ukraine forces are taking back their own land in lightning strikes.

It may be that the worst of the war is… over.

Perhaps only Wagner mercs were really still fighting at all, at the front.

And they’ve redeployed to merc bases, inside Russia.

So… yep, who knows?

Out.