EU Regulator Decides Against Tecovirimat SIGA, As An Mpox Therapeutic…

As we mentioned last month, the would-be treatment did no better than placebos, in animal models — CHMP has declared, at the EMA.

No double-blinded human trials were run, as there were too few Mpox patients (at the time) to evaluate it against.

The path of bio-science is inexorably littered with blind alley detours, as here.

Here’s all of that — from MedScape:

…The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended that Tecovirimat SIGA should no longer be used for the treatment of mpox.

A review of the antiviral medicine was initiated at the request of the European Commission following evidence from clinical trials suggesting a lack of effectiveness in the treatment of mpox. The CHMP’s decision does not affect the drugs other uses, including in the treatment of smallpox, cowpox, and complications from smallpox vaccines….

Onward, smiling — to a 90 minute isolation/flotation tank this afternoon [I will report here, scientifically if I am able to regress — to some primordial soup state(!)] — then the NCAAs tonight with buddies (at the United Center!), and “No Kings” again marching, down in the 40 degree Chi weather, tomorrow!

नमस्ते

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